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Image Search Results
Journal: Cell reports
Article Title: linc-ADAIN , a human adipose lincRNA, regulates adipogenesis by modulating KLF5 and IL-8 mRNA stability
doi: 10.1016/j.celrep.2024.114240
Figure Lengend Snippet: (A and B) ASC adipocytes with scramble or linc-ADAIN shRNA were implanted into the flanks of NSG mice and removed 16 weeks later. H&E staining of scramble and linc-ADAIN -KD implants after 16 weeks (scale bar, 60 μm) (A) and size distribution of adipocytes, quantified with Adiposoft in a 300 × 300 μm section (B). (C and D) CD68 (C) and F4/80 (D) IHC staining area quantified.
(E–K) Gene expression of mouse Cd68 (E) and Adgre1 (F) and human expression of IL-8 (G), MCP-1 (H), IL-6 (I), KLF5 (J), and PPARγ and CEBPα (K) in the scramble and linc-ADAIN shRNA-expressing explants after 16 weeks or the ASC hTERT adipocytes prior to implantation ( N = 4–7); * p < 0.05, ** p < 0.01, *** p < 0.001 with relation to scramble shRNA explant; ## p < 0.01 with relation to linc-ADAIN shRNA explant; $ $ $ p < 0.01 with reslation to scramble shRNA adipocytes by two-way ANOVA. Data are presented as the mean ± SEM.Article Snippet: Adipose Explant macrophage gene expression was assessed using mouse specific TaqMan primers (
Techniques: shRNA, Staining, Immunohistochemistry, Gene Expression, Expressing
Journal: Cell reports
Article Title: linc-ADAIN , a human adipose lincRNA, regulates adipogenesis by modulating KLF5 and IL-8 mRNA stability
doi: 10.1016/j.celrep.2024.114240
Figure Lengend Snippet:
Article Snippet: Adipose Explant macrophage gene expression was assessed using mouse specific TaqMan primers (
Techniques: Virus, Plasmid Preparation, Recombinant, Gene Expression, shRNA, Mass Spectrometry, Negative Control, Software, Modification, Magnetic Beads, RNAscope, Multiplex Assay, Western Blot